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1.
Braz. J. Pharm. Sci. (Online) ; 58: e19494, 2022. tab, graf
Article in English | LILACS | ID: biblio-1384024

ABSTRACT

Abstract The aim of this paper is to study the chemical composition of alkaloids present in Haloxylon scoparium Pomel extracts and to evaluate their antioxidant capacity. The alkaloids were isolated from two parts of Haloxylon scoparium plant by two extraction protocols. and The quantitative study made it possible to propose the best protocol for the extraction of the alkaloids. Moreover, GC-MS analysis of alkaloid extracts allowed us to determine their chemical composition. Haloxylon scoparium contains four types of alkaloids: tetraisoquinolines, phenylethylamines, tryptolines and tryptamines. The main compounds are the tetraisoquinolines type, the predominant product of which was N-methylsalsoline. These compounds present a great interest for the researchers due to their various pharmacological and biological activities. The antioxidant effect of the different plant extracts was studied by two methods: the ferric reducing antioxidant power (FRAP) and 1,1-diphenyl-2-picryl hydrazyl free radical (DPPH·) scavenging tests. The results show that extracts of root part are more active than those from aerial part; the acetone/water extract is the most powerful. The interesting results obtained in this study will be supplemented by other analyses and biological tests in order to better valorize this plant.


Subject(s)
Amaranthaceae/anatomy & histology , Alkaloids/chemical synthesis , Morocco/ethnology , Antioxidants/analysis , Plant Extracts/analysis , Fluorescence Recovery After Photobleaching/methods
2.
Rev. bras. toxicol ; 12(2): 55-62, dez. 1999. ilus, tab
Article in Portuguese | LILACS | ID: lil-282948

ABSTRACT

Este trabalho foi desenvolvido com o objetivo de identificar os princípios tóxicos da tetrapterys multigalndulosa A. Juss. Realizou-se triagem fitoquímica nas folhas (brotos e maduras) frescas, através de marcha analítica clássica e Cromatografia em Camada Delgada (CCD) pesquisando-se os seguintes princípios ativos: heterosídeos antrasênicos, saponínicos, flavônicos, cardiotônicos, taninos (hidrolisáveis e condensados), alcalóides (terciários e quaternários), composto esteróides e cumarínicos. Os resultados obtidos mostraram na folha jovem e madura, presença de heterosídeos flavônicos e esteróides. Taninos condensados e alcalóides quaternários foram encontrados somente na folha madura.


Subject(s)
Plant Extracts/analysis , Plant Leaves/chemistry , Plant Shoots/chemistry , Plants, Toxic/chemistry , Alkaloids/chemical synthesis , Anthracenes/chemical synthesis , Cardiac Glycosides/chemical synthesis , Cardiotonic Agents/chemical synthesis , Chromatography, Thin Layer , Coumarins/chemical synthesis , Flavones/chemical synthesis , Saponins/chemical synthesis , Steroids/chemical synthesis , Tannins/chemical synthesis
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